Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) (UG3/UH3 Clinical Trial Optional)


This Funding Opportunity Announcement (FOA) invites applications for projects that propose to test late-stage (T4) implementation research strategies for optimally and sustainably delivering proven-effective, evidence-based multi–level interventions to reduce or eliminate cardiovascular and/or pulmonary health disparities, and that promote and improve population health in high-burden communities. For the purpose of this FOA, late-stage (T4) implementation research is defined as research to identify strategies to achieve sustainable uptake of proven-effective interventions in routine clinical and public health practice and community-based settings and maximize the positive impact on population health .

This FOA uses the bi-phasic, milestone-driven UG3/UH3 cooperative agreement mechanism and runs in parallel with a companion FOA ( RFA-HL-20-004 ), which seeks applications for a Research Coordinating Center (RCC).  Awards made under this FOA will initially support a milestone-driven needs assessment and planning phase for up to three years, with possible transition to an implementation (UH3) phase of up to four additional years.  Only UG3 projects that meet the scientific milestones and award requirements of the UG3 phase may transition to the UH3 phase.  Applications submitted in response to this FOA must address both the UG3 and UH3 phases and are expected to include plans for project management and performance milestones for each phase.

Receipt Date:

Expires: April 17, 2019

Total Awards:

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

NHLBI intends to fund up to 8 awards, corresponding to total costs of up to $7,875,000 in FY 2020 and $10,500,000 per year in FY 2021 through 2026.


Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-20-003.html